BDBM50120268 CHEMBL421605::N-[2-(4-Bromo-phenyl)-2-oxo-ethyl]-3-(2,4-dioxo-3,4,5,6,7,8-hexahydro-2H-quinazolin-1-yl)-propionamide

SMILES Brc1ccc(cc1)C(=O)CNC(=O)CCn1c2CCCCc2c(=O)[nH]c1=O

InChI Key InChIKey=ATJQMIAIWKHJSS-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50120268   

TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Bayer

Curated by ChEMBL
LigandPNGBDBM50120268(CHEMBL421605 | N-[2-(4-Bromo-phenyl)-2-oxo-ethyl]-...)
Affinity DataEC50:  900nMAssay Description:Concentration required to inhibit human recombinant PARP-1 was determined using cell protection assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Bayer

Curated by ChEMBL
LigandPNGBDBM50120268(CHEMBL421605 | N-[2-(4-Bromo-phenyl)-2-oxo-ethyl]-...)
Affinity DataIC50:  80nMAssay Description:Inhibitory activity against human recombinant PARP-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed