BDBM50148942 CHEMBL3769902

SMILES Nc1ncc(cn1)-c1nc(N2CCOCC2)c2ccc(Nc3cccnc3C#N)cc2n1

InChI Key InChIKey=IOWVRIYKSLICNE-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50148942   

LigandPNGBDBM50148942(CHEMBL3769902)
Affinity DataIC50: 4.20nMAssay Description:Inhibition of PI3K alpha (unknown origin) using PIP2 as substrate after 1 hr by kinase-Glo luminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2017
Entry Details Article
PubMed
LigandPNGBDBM50148942(CHEMBL3769902)
Affinity DataIC50: 13nMAssay Description:Inhibition of PI3K beta (unknown origin) after 1 hr by ADP-Glo luminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2017
Entry Details Article
PubMed
LigandPNGBDBM50148942(CHEMBL3769902)
Affinity DataIC50: 50nMAssay Description:Inhibition of PI3K delta (unknown origin) using PIP2 as substrate after 1 hr by kinase-Glo luminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2017
Entry Details Article
PubMed
LigandPNGBDBM50148942(CHEMBL3769902)
Affinity DataIC50: 64nMAssay Description:Inhibition of PI3K gamma (unknown origin) after 1 hr by ADP-Glo luminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2017
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50148942(CHEMBL3769902)
Affinity DataIC50: 78nMAssay Description:Inhibition of mTOR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2017
Entry Details Article
PubMed