BDBM50151188 5-(4-((5-chloro-1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)methyl)piperazin-1-yl)-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-7-amine::5-[4-(5-Chloro-1-methyl-3-trifluoromethyl-1H-pyrazol-4-ylmethyl)-piperazin-1-yl]-2-furan-2-yl-[1,2,4]triazolo[1,5-a][1,3,5]triazin-7-ylamine::CHEMBL189192

SMILES Cn1nc(c(CN2CCN(CC2)c2nc(N)n3nc(nc3n2)-c2ccco2)c1Cl)C(F)(F)F

InChI Key InChIKey=BTPRCXIXYZWERG-UHFFFAOYSA-N

Data  10 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50151188   

TargetAdenosine receptor A2a(Rattus norvegicus (rat))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50151188(5-(4-((5-chloro-1-methyl-3-(trifluoromethyl)-1H-py...)
Affinity DataKi:  14nMAssay Description:Displacement of [3H]ZM241385 from adenosine A2A receptor in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Rattus norvegicus (rat))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50151188(5-(4-((5-chloro-1-methyl-3-(trifluoromethyl)-1H-py...)
Affinity DataKi:  14nMAssay Description:Inhibition of [3H]-ZM-241,385 binidng to rat brain adenosine A2a receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50151188(5-(4-((5-chloro-1-methyl-3-(trifluoromethyl)-1H-py...)
Affinity DataKi:  100nMAssay Description:Antagonist activity at human adenosine A2A receptorMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50151188(5-(4-((5-chloro-1-methyl-3-(trifluoromethyl)-1H-py...)
Affinity DataKi:  100nMAssay Description:Selectivity for recombinant human adenosine A2a receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50151188(5-(4-((5-chloro-1-methyl-3-(trifluoromethyl)-1H-py...)
Affinity DataKi:  1.10E+3nMAssay Description:Displacement of [3h]DPCPX from adenosine A receptor in rat cerebral cortex membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50151188(5-(4-((5-chloro-1-methyl-3-(trifluoromethyl)-1H-py...)
Affinity DataKi:  1.10E+3nMAssay Description:Inhibition of [3H]-DPCPX binding to rat cerebral cortex adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50151188(5-(4-((5-chloro-1-methyl-3-(trifluoromethyl)-1H-py...)
Affinity DataKi:  1.00E+4nMAssay Description:Antagonist activity at human adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50151188(5-(4-((5-chloro-1-methyl-3-(trifluoromethyl)-1H-py...)
Affinity DataKi: >1.00E+4nMAssay Description:Selectivity for recombinant human adenosine A3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50151188(5-(4-((5-chloro-1-methyl-3-(trifluoromethyl)-1H-py...)
Affinity DataKi:  1.00E+4nMAssay Description:Selectivity for recombinant human adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50151188(5-(4-((5-chloro-1-methyl-3-(trifluoromethyl)-1H-py...)
Affinity DataKi:  2.80E+4nMAssay Description:Selectivity for recombinant human adenosine A2b receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed