BDBM50151659 CHEMBL3775244

SMILES COc1ccc(cc1OC)C1CC(=NN1c1nc(cs1)-c1ccc(cc1)N1C(=O)c2ccccc2C1=O)c1cccs1

InChI Key InChIKey=UOEGYWWWSHVNGP-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50151659   

TargetHistone acetyltransferase p300(Homo sapiens (Human))
University Of Freiburg

Curated by ChEMBL
LigandPNGBDBM50151659(CHEMBL3775244)
Affinity DataIC50:  1.50E+5nMAssay Description:Inhibition of p300 (unknown origin) using N-terminal histone H4-20 peptide substrate incubated for 10 mins by liquid scintillation counting method in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSpermidine synthase(Sus scrofa)
University Of Freiburg

Curated by ChEMBL
LigandPNGBDBM50151659(CHEMBL3775244)
Affinity DataIC50:  1.90E+5nMAssay Description:Inhibition of yeast ESA1 using N-terminal histone H3 substrate by radiometric filter binding based virtual screen in presence of [3H]acetyl-CoAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone acetyltransferase KAT5(Homo sapiens (Human))
University Of Freiburg

Curated by ChEMBL
LigandPNGBDBM50151659(CHEMBL3775244)
Affinity DataIC50:  1.49E+5nMAssay Description:Inhibition of full length TIP60 (unknown origin) expressed in Escherichia coli using N-terminal histone H4-20 peptide substrate incubated for 10 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone acetyltransferase KAT2B(Homo sapiens (Human))
University Of Freiburg

Curated by ChEMBL
LigandPNGBDBM50151659(CHEMBL3775244)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of PCAF (unknown origin) using N-terminal histone H3-20 peptide substrate incubated for 3.5 mins by liquid scintillation counting method i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed