BDBM50155776 (S)-3,10-Dibromo-8-chloro-11-(1-methanesulfonyl-piperidin-4-yl)-11H-benzo[5,6]cyclohepta[1,2-b]pyridine::CHEMBL365463

SMILES CS(=O)(=O)N1CCC(CC1)[C@@H]1c2ncc(Br)cc2C=Cc2cc(Cl)cc(Br)c12

InChI Key InChIKey=RWNAKQQQDZHREQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50155776   

TargetDimer of Protein farnesyltransferase subunit beta(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50155776((S)-3,10-Dibromo-8-chloro-11-(1-methanesulfonyl-pi...)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of [3H]FPP incorporation into H-ras CVLS by FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed