BDBM50156718 1-(4-bromobenzyl)-4-(4-butoxyphenylsulfonyl)-N-hydroxypiperidine-4-carboxamide::CHEMBL222934

SMILES CCCCOc1ccc(cc1)S(=O)(=O)C1(CCN(Cc2ccc(Br)cc2)CC1)C(=O)NO

InChI Key InChIKey=YJZSNVXLDDRADS-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50156718   

TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50156718(1-(4-bromobenzyl)-4-(4-butoxyphenylsulfonyl)-N-hyd...)
Affinity DataIC50:  10nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50156718(1-(4-bromobenzyl)-4-(4-butoxyphenylsulfonyl)-N-hyd...)
Affinity DataIC50:  72nMAssay Description:Inhibition of TACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50156718(1-(4-bromobenzyl)-4-(4-butoxyphenylsulfonyl)-N-hyd...)
Affinity DataIC50:  5nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50156718(1-(4-bromobenzyl)-4-(4-butoxyphenylsulfonyl)-N-hyd...)
Affinity DataIC50:  3.96E+3nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed