BDBM50156726 2-{[4-(2-butynyloxy)phenyl]sulfonyl}-N-hydroxy-2-(1-oxidotetrahydro-4H-thiopyran-4-yl)acetamide::CHEMBL222303

SMILES CC#CCOc1ccc(cc1)S(=O)(=O)C(C1CCS(=O)CC1)C(=O)NO

InChI Key InChIKey=NPIXRIRDKCZNLD-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50156726   

TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50156726(2-{[4-(2-butynyloxy)phenyl]sulfonyl}-N-hydroxy-2-(...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50156726(2-{[4-(2-butynyloxy)phenyl]sulfonyl}-N-hydroxy-2-(...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50156726(2-{[4-(2-butynyloxy)phenyl]sulfonyl}-N-hydroxy-2-(...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50156726(2-{[4-(2-butynyloxy)phenyl]sulfonyl}-N-hydroxy-2-(...)
Affinity DataIC50:  39nMAssay Description:Inhibition of TACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed