BDBM50157973 5-chloro-thiophene-2-sulfonic acid tricyclo[8.2.1.0*3,8*]trideca-3(8),4,6-trien-13-ylamide::CHEMBL183777

SMILES Clc1ccc(s1)S(=O)(=O)NC1C2CCC1Cc1ccccc1C2

InChI Key InChIKey=DIGSRNGZVYWJEK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50157973   

TargetPresenilin-1(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50157973(5-chloro-thiophene-2-sulfonic acid tricyclo[8.2.1....)
Affinity DataIC50:  63nMAssay Description:Inhibition of human gamma secretase in human SHSY5Y cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50157973(5-chloro-thiophene-2-sulfonic acid tricyclo[8.2.1....)
Affinity DataIC50:  62nMAssay Description:Inhibitory concentration against Gamma-secretase in whole cell inhibition assay using SH-SY5Y cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed