BDBM50159505 CHEMBL1779158::N,N-Dibenzyltryptamine

SMILES C(Cc1c[nH]c2ccccc12)N(Cc1ccccc1)Cc1ccccc1

InChI Key InChIKey=WEWPMAKQEUSKPV-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50159505   

TargetTransient receptor potential cation channel subfamily M member 8(Rattus norvegicus (Rat))
University Of Salerno

Curated by ChEMBL
LigandPNGBDBM50159505(CHEMBL1779158 | N,N-Dibenzyltryptamine)
Affinity DataIC50:  367nMAssay Description:Antagonist activity at rat TRPM8 expressed in HEK293 cells assessed as inhibition of menthol mediated current amplitude at +80 mV holding potential b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50159505(CHEMBL1779158 | N,N-Dibenzyltryptamine)
Affinity DataIC50:  800nMAssay Description:Antagonist activity at TRPM8 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50159505(CHEMBL1779158 | N,N-Dibenzyltryptamine)
Affinity DataIC50:  35nMAssay Description:Modulation of TRPV1 (unknown origin) by fluorometric imaging plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTransient receptor potential cation channel subfamily M member 8(Rattus norvegicus (Rat))
University Of Salerno

Curated by ChEMBL
LigandPNGBDBM50159505(CHEMBL1779158 | N,N-Dibenzyltryptamine)
Affinity DataIC50:  3.20E+3nMAssay Description:Antagonist activity at rat TRPM8 expressed in HEK293 cells assessed as reduction in menthol-induced calcium flux incubated for 60 mins by Fluo-4 NW-d...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed