BDBM50160028 CHEMBL180138::N-(4-tert-Butyl-phenyl)-4-(3-methyl-pyridin-2-yl)-benzamide::N-(4-tert-butylphenyl)-4-(3-methylpyridin-2-yl)benzamide

SMILES Cc1cccnc1-c1ccc(cc1)C(=O)Nc1ccc(cc1)C(C)(C)C

InChI Key InChIKey=HNENYCYVYIYIHV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50160028   

TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Neurogen

Curated by ChEMBL
LigandPNGBDBM50160028(CHEMBL180138 | N-(4-tert-Butyl-phenyl)-4-(3-methyl...)
Affinity DataIC50:  11nMAssay Description:Antagonist activity against capsaicin-activated human VR1 by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Neurogen

Curated by ChEMBL
LigandPNGBDBM50160028(CHEMBL180138 | N-(4-tert-Butyl-phenyl)-4-(3-methyl...)
Affinity DataIC50:  9nMAssay Description:Antagonist activity against low pH(5.0-5.5)-activated rat VR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Neurogen

Curated by ChEMBL
LigandPNGBDBM50160028(CHEMBL180138 | N-(4-tert-Butyl-phenyl)-4-(3-methyl...)
Affinity DataIC50:  31nMAssay Description:In vitro antagonistic activity on VR1 receptor in [Ca2+] influx assay in rat dorsal root ganglionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed