BDBM50164398 CHEMBL3799213
SMILES FC(F)(F)c1cc(Cl)n(Cc2cc(=O)n3c([C@@H]4C[C@H]4C#N)c(sc3n2)C(F)(F)F)n1
InChI Key InChIKey=FTIBNGABJNFFAI-POYBYMJQSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50164398
Affinity DataEC50: 9.10E+3nMAssay Description:Positive allosteric modulation of human GluA2 AMPAR flip isomer expressed in Dox-inducible cells measured every 5 mins by BD calcium indicator dye ba...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2C(Homo sapiens (Human))
Pharmaron-Beijing
Curated by ChEMBL
Pharmaron-Beijing
Curated by ChEMBL
Affinity DataEC50: 7.40E+3nMAssay Description:Positive allosteric modulation of GluN1/GluN2C NMDAR (unknown origin) expressed in Dox-inducible cells by BD calcium indicator dye based-fluorescence...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2D(Homo sapiens (Human))
Pharmaron-Beijing
Curated by ChEMBL
Pharmaron-Beijing
Curated by ChEMBL
Affinity DataEC50: 6.20E+3nMAssay Description:Positive allosteric modulation of GluN1/GluN2D NMDAR (unknown origin) expressed in Dox-inducible cells by BD calcium indicator dye based-fluorescence...More data for this Ligand-Target Pair
Affinity DataEC50: 5.50E+3nMAssay Description:Positive allosteric modulation of human GluA2 AMPAR flop isomer expressed in Dox-inducible cells measured every 5 mins by BD calcium indicator dye ba...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2A(Homo sapiens (Human))
Pharmaron-Beijing
Curated by ChEMBL
Pharmaron-Beijing
Curated by ChEMBL
Affinity DataEC50: 21nMAssay Description:Positive allosteric modulation of GluN1/GluN2A NMDAR (unknown origin) expressed in Dox-inducible cells measured every 5 mins by BD calcium indicator ...More data for this Ligand-Target Pair