BDBM50171817 3-(4-((1-(4-tert-butylcyclohexyl)-3-(4-(trifluoromethoxy)phenyl)ureido)methyl)benzamido)propanoic acid::3-{4-[1-(4-tert-Butyl-cyclohexyl)-3-(4-trifluoromethoxy-phenyl)-ureidomethyl]-benzoylamino}-propionic acid::CHEMBL198736

SMILES CC(C)(C)C1CCC(CC1)N(Cc1ccc(cc1)C(=O)NCCC(O)=O)C(=O)Nc1ccc(OC(F)(F)F)cc1

InChI Key InChIKey=BZXMLCVDKDXRQY-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50171817   

TargetGlucagon receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50171817(3-(4-((1-(4-tert-butylcyclohexyl)-3-(4-(trifluorom...)
Affinity DataIC50:  21nMAssay Description:Antagonist activity against human glucagon receptor expressed in CHO cell membranes using [125I]glucagonMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50171817(3-(4-((1-(4-tert-butylcyclohexyl)-3-(4-(trifluorom...)
Affinity DataIC50:  2.54E+3nMAssay Description:Binding affinity to human cloned GLP1R expressed in BHK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50171817(3-(4-((1-(4-tert-butylcyclohexyl)-3-(4-(trifluorom...)
Affinity DataIC50:  144nMAssay Description:Inhibitory concentration against glucagon-induced cAMP accumulation in human glucagon receptor transfected CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastric inhibitory polypeptide receptor(Rattus norvegicus)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50171817(3-(4-((1-(4-tert-butylcyclohexyl)-3-(4-(trifluorom...)
Affinity DataIC50:  42nMAssay Description:Binding affinity to GIPR in rat liver membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastric inhibitory polypeptide receptor(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50171817(3-(4-((1-(4-tert-butylcyclohexyl)-3-(4-(trifluorom...)
Affinity DataIC50:  28nMAssay Description:Binding affinity to human cloned GIPR expressed in BHK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Rattus norvegicus)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50171817(3-(4-((1-(4-tert-butylcyclohexyl)-3-(4-(trifluorom...)
Affinity DataIC50:  23nMAssay Description:Binding affinity to GlucR in rat liver membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50171817(3-(4-((1-(4-tert-butylcyclohexyl)-3-(4-(trifluorom...)
Affinity DataIC50:  23nMAssay Description:Binding affinity to human cloned GluR expressed in BHK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed