BDBM50174281 4-methyl-3-(4-pentylbicyclo[2.2.2]octan-1-yl)-5-(2-(trifluoromethyl)phenyl)-4H-1,2,4-triazole::CHEMBL383352
SMILES CCCCCC12CCC(CC1)(CC2)c1nnc(-c2ccccc2C(F)(F)F)n1C
InChI Key InChIKey=VPHWCVUMWQOWOK-UHFFFAOYSA-N
Data 7 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50174281
Affinity DataIC50: 3nMAssay Description:Inhibitory activity against mouse 11beta-HSD1More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibitory activity against human 11beta-HSD1More data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human 11beta-HSD2 expressed in CHO-K1 cells assessed as conversion of [3H]-cortisol to [3H]-cortisone by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of 11beta-HSD1More data for this Ligand-Target Pair
Affinity DataIC50: 1.80nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO-K1 cells assessed as conversion of [3H]-cortisone to [3H]-cortisol by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO-K1 cells assessed as conversion of [3H]-cortisone to [3H]-cortisol by scintillation proximity assayMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase type 2(Mus musculus (mouse))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: >4.00E+3nMAssay Description:Inhibition of mouse 11beta-HSD2 expressed in CHO-K1 cells assessed as conversion of [3H]-cortisol to [3H]-cortisone by scintillation proximity assayMore data for this Ligand-Target Pair