BDBM50175225 CHEMBL3808606

SMILES Cc1cc(C)c(Nc2ccc(Cl)c(c2)C(F)(F)F)c(C)c1

InChI Key InChIKey=FLFWWGQQNBDVES-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50175225   

TargetRap guanine nucleotide exchange factor 4(Homo sapiens (Human))
University Of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50175225(CHEMBL3808606)
Affinity DataIC50:  400nMAssay Description:Inhibition of 8-NBD-cAMP binding to EPAC2 (unknown origin) by microplate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRap guanine nucleotide exchange factor 4(Homo sapiens (Human))
University Of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50175225(CHEMBL3808606)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of EPAC2 (unknown origin) assessed as reduction in cAMP-mediated guanine nucleotide exchange factor activity in presence of C-terminal tru...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed