BDBM50180423 (8-Bromo-10,11-dihydro-5-oxa-2,4,11-triaza-dibenzo[a,d]cyclohepten-1-yl)-(3-chloro-4-fluoro-phenyl)-amine::CHEMBL206280

SMILES Fc1ccc(Nc2ncnc3Oc4ccc(Br)cc4CNc23)cc1Cl

InChI Key InChIKey=RXSWGOQRLDFWFT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50180423   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Imclone Systems

Curated by ChEMBL
LigandPNGBDBM50180423((8-Bromo-10,11-dihydro-5-oxa-2,4,11-triaza-dibenzo...)
Affinity DataIC50:  8.40E+3nMAssay Description:Inhibition of EGFR autophosphorylation in DiFi cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Imclone Systems

Curated by ChEMBL
LigandPNGBDBM50180423((8-Bromo-10,11-dihydro-5-oxa-2,4,11-triaza-dibenzo...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed