BDBM50192479 (5-chloro-2-fluoro-phenyl)-(7,8-dimethoxy-10,11-dihydro-5-oxa-2,4,11-triaza-dibenzo[a,d]cyclohepten-1-yl)-amine::CHEMBL214753
SMILES COc1cc2CNc3c(Nc4cc(Cl)ccc4F)ncnc3Oc2cc1OC
InChI Key InChIKey=WCMSKFSDZXTGKD-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50192479
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of EGFR measured as pGAT-biotin peptide phosphorylation in presence of 2.0 uM ATP by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of EGFR autophosphorylation in DiFi cells by ELISAMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Imclone Systems
Curated by ChEMBL
Imclone Systems
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of KDR measured as pGAT-biotin peptide phosphorylation by HTRF assayMore data for this Ligand-Target Pair