BDBM50197971 CHEMBL3890789

SMILES CC(C)[C@@]12CC[C@@](C)(O1)[C@H](CC\C(C)=C\CC\C(C)=C\C2)OC(=O)Cc1ccccc1

InChI Key InChIKey=QCWPMFRYVOOFJC-UKTRBUHOSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50197971   

TargetHeat sensitive channel TRPV3(Rattus norvegicus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50197971(CHEMBL3890789)
Affinity DataIC50:  2.17E+4nMAssay Description:Antagonist activity at rat TRPV3 overexpressed in HEK293 cells assessed as inhibition of thymol-induced increase in intracellular Ca2+ levels preincu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50197971(CHEMBL3890789)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of IFNgamma-induced STAT3 activation in human HeLa cells expressing STAT3 (unknown origin) preincubated for 15 mins followed by IFN-gamma ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat sensitive channel TRPV3(Rattus norvegicus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50197971(CHEMBL3890789)
Affinity DataEC50:  1.20E+3nMAssay Description:Activation of rat TRPV3 overexpressed in HEK293 cells assessed as increase in 2-aminoethoxydiphenyl borate-induced intracellular calcium concentratio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed