BDBM50203562 4-((6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)methyl)-N-(2-(dimethylamino)ethyl)-7-methoxybenzofuran-2-carboxamide::CHEMBL428407

SMILES COc1cc2CCN(Cc3ccc(OC)c4oc(cc34)C(=O)NCCN(C)C)Cc2cc1OC

InChI Key InChIKey=IWHCCXKZMXALTR-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50203562   

TargetAlpha-2C adrenergic receptor(Human)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50203562(4-((6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)...)
Affinity DataKi:  9.40nMAssay Description:Displacement of [3H]MK912 from adrenergic Alpha-2C receptor in HepG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Human)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50203562(4-((6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)...)
Affinity DataKi:  454nMAssay Description:Displacement of [3H]MK-912 from adrenergic alpha2A receptor in HT29 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetAlpha-2B adrenergic receptor(Human)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50203562(4-((6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)...)
Affinity DataKi:  2.07E+3nMAssay Description:Displacement of [3H]MK912 from adrenergic alpha-2B receptor expressed in COS7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed