BDBM50209211 3,8-dibromoboldine::CHEMBL388564

SMILES COc1cc-2c(C[C@@H]3N(C)CCc4c(Br)c(O)c(OC)c-2c34)c(Br)c1O

InChI Key InChIKey=FTUCKVYWXINSAK-UHFFFAOYSA-N

Data  2 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50209211   

TargetD(1A) dopamine receptor(Rat)
Universidad De Chile

Curated by ChEMBL
LigandPNGBDBM50209211(3,8-dibromoboldine | CHEMBL388564)
Affinity DataIC50: 206nMAssay Description:Displacement of [3H]SCH23390 from dopamine D1 receptor in Wistar rat striatal membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Universidad De Chile

Curated by ChEMBL
LigandPNGBDBM50209211(3,8-dibromoboldine | CHEMBL388564)
Affinity DataIC50: 1.91E+3nMAssay Description:Displacement of [3H]raclopride from dopamine D2 receptor in Wistar rat striatal membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
University of Chile

Curated by ChEMBL
LigandPNGBDBM50209211(3,8-dibromoboldine | CHEMBL388564)
Affinity DataKi:  3.10E+4nMAssay Description:Displacement of [3H]cytisine from human alpha-4-beta-2 nAChR expressed in SH-EP1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
University of Chile

Curated by ChEMBL
LigandPNGBDBM50209211(3,8-dibromoboldine | CHEMBL388564)
Affinity DataKi:  9.50E+4nMAssay Description:Displacement of [125I]alpha-bungarotoxin from human alpha-7 nAChR expressed in SH-SY5Y cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
University of Chile

Curated by ChEMBL
LigandPNGBDBM50209211(3,8-dibromoboldine | CHEMBL388564)
Affinity DataIC50: 1.01E+5nMAssay Description:Displacement of [3H]cytisine from human alpha-4-beta-2 nAChR expressed in SH-EP1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
University of Chile

Curated by ChEMBL
LigandPNGBDBM50209211(3,8-dibromoboldine | CHEMBL388564)
Affinity DataIC50: 1.14E+5nMAssay Description:Displacement of [125I]alpha-bungarotoxin from human alpha-7 nAChR expressed in SH-SY5Y cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed