BDBM50209350 CHEMBL388483::N-(2,6-difluorophenyl)-4-(2-methyl-4-(6-(3-morpholinopropoxy)quinazolin-4-ylamino)phenoxy)piperidine-1-carboxamide

SMILES Cc1cc(Nc2ncnc3ccc(OCCCN4CCOCC4)cc23)ccc1OC1CCN(CC1)C(=O)Nc1c(F)cccc1F

InChI Key InChIKey=LJZIMCVKWDQQNE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50209350   

TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50209350(CHEMBL388483 | N-(2,6-difluorophenyl)-4-(2-methyl-...)
Affinity DataIC50:  55nMAssay Description:Inhibition of erbB2 in NH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50209350(CHEMBL388483 | N-(2,6-difluorophenyl)-4-(2-methyl-...)
Affinity DataIC50:  55nMAssay Description:Inhibition of erbB2 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed