BDBM50209351 CHEMBL230575::N-(3-(4-(4-(1-(3,3-dimethylbutanoyl)piperidin-4-yloxy)-3-methylphenylamino)quinazolin-6-yl)prop-2-ynyl)-2-methoxyacetamide

SMILES COCC(=O)NCC#Cc1ccc2ncnc(Nc3ccc(OC4CCN(CC4)C(=O)CC(C)(C)C)c(C)c3)c2c1

InChI Key InChIKey=WYWVXEDYXGGHGR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50209351   

TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50209351(CHEMBL230575 | N-(3-(4-(4-(1-(3,3-dimethylbutanoyl...)
Affinity DataIC50:  16nMAssay Description:Inhibition of erbB2 in NH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50209351(CHEMBL230575 | N-(3-(4-(4-(1-(3,3-dimethylbutanoyl...)
Affinity DataIC50:  94nMAssay Description:Inhibition of erbB2 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed