BDBM50209355 4-(4-(6,7-dimethoxyquinazolin-4-ylamino)-2-methylphenoxy)-N-neopentylbenzamide::CHEMBL387543

SMILES COc1cc2ncnc(Nc3ccc(Oc4ccc(cc4)C(=O)NCC(C)(C)C)c(C)c3)c2cc1OC

InChI Key InChIKey=GPDZPPBNVFQOCS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50209355   

TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50209355(4-(4-(6,7-dimethoxyquinazolin-4-ylamino)-2-methylp...)
Affinity DataIC50:  77nMAssay Description:Inhibition of erbB2 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50209355(4-(4-(6,7-dimethoxyquinazolin-4-ylamino)-2-methylp...)
Affinity DataIC50:  310nMAssay Description:Inhibition of erbB2 in NH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed