BDBM50210953 (1R,2S,3R,5R)-methyl 3-(4-ethynylphenyl)-8-aza-bicyclo[3.2.1]octane-2-carboxylate::CHEMBL394158

SMILES COC(=O)[C@@H]1[C@H]2CC[C@H](C[C@H]1c1ccc(cc1)C#C)N2

InChI Key InChIKey=TYFSSZYOVLRLQK-QXSJWSMHSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50210953   

TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50210953((1R,2S,3R,5R)-methyl 3-(4-ethynylphenyl)-8-aza-bic...)
Affinity DataKi:  1.86nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50210953((1R,2S,3R,5R)-methyl 3-(4-ethynylphenyl)-8-aza-bic...)
Affinity DataKi:  2.26nMAssay Description:Displacement of [125I]RTI55 from human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50210953((1R,2S,3R,5R)-methyl 3-(4-ethynylphenyl)-8-aza-bic...)
Affinity DataKi:  3.45nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed