BDBM50210954 (1R,2S,3R,5R)-methyl 3-(3-fluoro-4-methylphenyl)-8-aza-bicyclo[3.2.1]octane-2-carboxylate::CHEMBL391864

SMILES COC(=O)[C@@H]1[C@H]2CC[C@H](C[C@H]1c1ccc(C)c(F)c1)N2

InChI Key InChIKey=QDZIBQWKRRRXAL-OSRDXIQISA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50210954   

TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50210954((1R,2S,3R,5R)-methyl 3-(3-fluoro-4-methylphenyl)-8...)
Affinity DataKi:  1.78nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50210954((1R,2S,3R,5R)-methyl 3-(3-fluoro-4-methylphenyl)-8...)
Affinity DataKi:  6.42nMAssay Description:Displacement of [125I]RTI55 from human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50210954((1R,2S,3R,5R)-methyl 3-(3-fluoro-4-methylphenyl)-8...)
Affinity DataKi:  42.8nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed