BDBM50211003 CHEMBL243141::ethyl 4-(3,4-dichlorophenyl)-1,2,5,6-tetrahydropyridine-3-carboxylate

SMILES CCOC(=O)C1=C(CCNC1)c1ccc(Cl)c(Cl)c1

InChI Key InChIKey=GKCCZGXUGNBNGL-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50211003   

TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
University Of Aarhus

Curated by ChEMBL
LigandPNGBDBM50211003(CHEMBL243141 | ethyl 4-(3,4-dichlorophenyl)-1,2,5,...)
Affinity DataKi:  217nMAssay Description:Displacement of [125I]RTI55 from human SERT expressed in COS1 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
University Of Aarhus

Curated by ChEMBL
LigandPNGBDBM50211003(CHEMBL243141 | ethyl 4-(3,4-dichlorophenyl)-1,2,5,...)
Affinity DataKi:  922nMAssay Description:Displacement of [125I]RTI55 from human DAT expressed in COS1 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
University Of Aarhus

Curated by ChEMBL
LigandPNGBDBM50211003(CHEMBL243141 | ethyl 4-(3,4-dichlorophenyl)-1,2,5,...)
Affinity DataKi:  2.50E+3nMAssay Description:Displacement of [125I]RTI55 from human NET expressed in COS1 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed