BDBM50211027 CHEMBL394585::methyl 2-(4-chlorophenyl)cyclopent-1-enecarboxylate

SMILES COC(=O)C1=C(CCC1)c1ccc(Cl)cc1

InChI Key InChIKey=FPYUHFVUAJRFHA-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50211027   

TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
University Of Aarhus

Curated by ChEMBL
LigandPNGBDBM50211027(CHEMBL394585 | methyl 2-(4-chlorophenyl)cyclopent-...)
Affinity DataKi:  2.10E+3nMAssay Description:Inhibition of [3H]DA uptake in human DAT expressed in COS1 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
University Of Aarhus

Curated by ChEMBL
LigandPNGBDBM50211027(CHEMBL394585 | methyl 2-(4-chlorophenyl)cyclopent-...)
Affinity DataKi:  1.80E+4nMAssay Description:Displacement of [125I]RTI55 from human DAT expressed in COS1 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
University Of Aarhus

Curated by ChEMBL
LigandPNGBDBM50211027(CHEMBL394585 | methyl 2-(4-chlorophenyl)cyclopent-...)
Affinity DataKi:  1.78E+5nMAssay Description:Inhibition of [3H]DA uptake in human NET expressed in COS1 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
University Of Aarhus

Curated by ChEMBL
LigandPNGBDBM50211027(CHEMBL394585 | methyl 2-(4-chlorophenyl)cyclopent-...)
Affinity DataKi:  4.20E+5nMAssay Description:Displacement of [125I]RTI55 from human NET expressed in COS1 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
University Of Aarhus

Curated by ChEMBL
LigandPNGBDBM50211027(CHEMBL394585 | methyl 2-(4-chlorophenyl)cyclopent-...)
Affinity DataKi:  2.84E+6nMAssay Description:Displacement of [125I]RTI55 from human SERT expressed in COS1 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed