BDBM50211037 CHEMBL398009::methyl 2-(4-chlorophenyl)cyclohept-1-enecarboxylate

SMILES COC(=O)C1=C(CCCCC1)c1ccc(Cl)cc1

InChI Key InChIKey=KLBBBQNCHMPXRI-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50211037   

TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
University Of Aarhus

Curated by ChEMBL
LigandPNGBDBM50211037(CHEMBL398009 | methyl 2-(4-chlorophenyl)cyclohept-...)
Affinity DataKi:  2.20E+3nMAssay Description:Inhibition of [3H]DA uptake in human DAT expressed in COS1 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
University Of Aarhus

Curated by ChEMBL
LigandPNGBDBM50211037(CHEMBL398009 | methyl 2-(4-chlorophenyl)cyclohept-...)
Affinity DataKi:  1.50E+4nMAssay Description:Displacement of [125I]RTI55 from human DAT expressed in COS1 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
University Of Aarhus

Curated by ChEMBL
LigandPNGBDBM50211037(CHEMBL398009 | methyl 2-(4-chlorophenyl)cyclohept-...)
Affinity DataKi:  2.00E+4nMAssay Description:Inhibition of [3H]DA uptake in human NET expressed in COS1 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
University Of Aarhus

Curated by ChEMBL
LigandPNGBDBM50211037(CHEMBL398009 | methyl 2-(4-chlorophenyl)cyclohept-...)
Affinity DataKi:  8.40E+4nMAssay Description:Displacement of [125I]RTI55 from human NET expressed in COS1 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
University Of Aarhus

Curated by ChEMBL
LigandPNGBDBM50211037(CHEMBL398009 | methyl 2-(4-chlorophenyl)cyclohept-...)
Affinity DataKi:  7.06E+5nMAssay Description:Displacement of [125I]RTI55 from human SERT expressed in COS1 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed