BDBM50211840 2-(2-fluoro-4-chlorophenylamino)-4-trifluoromethyl-pyrimidine-5-carboxylic acid (tetrahydro-pyran-4-ylmethyl)amide::CHEMBL225465

SMILES Fc1cc(Cl)ccc1Nc1ncc(C(=O)NCC2CCOCC2)c(n1)C(F)(F)F

InChI Key InChIKey=WTDJZXIANMNOOX-UHFFFAOYSA-N

Data  5 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50211840   

TargetCannabinoid receptor 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50211840(2-(2-fluoro-4-chlorophenylamino)-4-trifluoromethyl...)
Affinity DataEC50:  200nMAssay Description:Agonist activity at human recombinant CB2 receptor expressed in Saccharomyces cerevisiae cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50211840(2-(2-fluoro-4-chlorophenylamino)-4-trifluoromethyl...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human CYP2C19More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50211840(2-(2-fluoro-4-chlorophenylamino)-4-trifluoromethyl...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50211840(2-(2-fluoro-4-chlorophenylamino)-4-trifluoromethyl...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50211840(2-(2-fluoro-4-chlorophenylamino)-4-trifluoromethyl...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50211840(2-(2-fluoro-4-chlorophenylamino)-4-trifluoromethyl...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human CYP1A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed