BDBM50211857 2-[(3-chlorophenyl)amino]-n-(4-pyridinylmethyl)-4-(trifluoromethyl)-5-pyrimidinecarboxamide::CHEMBL375955

SMILES FC(F)(F)c1nc(Nc2cccc(Cl)c2)ncc1C(=O)NCc1ccncc1

InChI Key InChIKey=HLCPJLIYGNWTAI-UHFFFAOYSA-N

Data  3 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50211857   

TargetCannabinoid receptor 1(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50211857(2-[(3-chlorophenyl)amino]-n-(4-pyridinylmethyl)-4-...)
Affinity DataEC50: >30nMAssay Description:Agonist activity at human CB1 receptor expressed in Saccharomyces cerevisiae MMY23 using fluorescein di-beta-D-glucopyranoside as substrate after 24 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50211857(2-[(3-chlorophenyl)amino]-n-(4-pyridinylmethyl)-4-...)
Affinity DataEC50:  50nMAssay Description:Agonist activity at human CB2 receptor expressed in Saccharomyces cerevisiae MMY23 using fluorescein di-beta-D-glucopyranoside as substrate after 24 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50211857(2-[(3-chlorophenyl)amino]-n-(4-pyridinylmethyl)-4-...)
Affinity DataEC50:  60nMAssay Description:Agonist activity at human recombinant CB2 receptor expressed in Saccharomyces cerevisiae cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50211857(2-[(3-chlorophenyl)amino]-n-(4-pyridinylmethyl)-4-...)
Affinity DataIC50: 400nMAssay Description:Inhibition of human CYP1A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50211857(2-[(3-chlorophenyl)amino]-n-(4-pyridinylmethyl)-4-...)
Affinity DataIC50: 900nMAssay Description:Inhibition of human CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50211857(2-[(3-chlorophenyl)amino]-n-(4-pyridinylmethyl)-4-...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of human CYP2C19More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed