BDBM50215756 6-methoxy-2-(4-(2-(4-methylpyridin-3-yl)vinyl)-1H-pyrazol-3-yl)-1H-benzo[d]imidazole::CHEMBL245574

SMILES COc1ccc2nc([nH]c2c1)-c1n[nH]cc1C=Cc1cnccc1C

InChI Key InChIKey=WZMDQWFGHYPLKD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50215756   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50215756(6-methoxy-2-(4-(2-(4-methylpyridin-3-yl)vinyl)-1H-...)
Affinity DataIC50:  760nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50215756(6-methoxy-2-(4-(2-(4-methylpyridin-3-yl)vinyl)-1H-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of HER2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50215756(6-methoxy-2-(4-(2-(4-methylpyridin-3-yl)vinyl)-1H-...)
Affinity DataIC50:  550nMAssay Description:Inhibition of aurora-AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed