BDBM50217776 CHEMBL397324::N-(2-bromo-4,5-dimethoxycinnamyl)-N-(4-((4-aminocyclohexyl)methyl)cyclohexyl)-4-(1H-indol-3-yl)butanamide

SMILES COc1cc(Br)c(\C=C\CN(C2CCC(CC3CCC(N)CC3)CC2)C(=O)CCCc2c[nH]c3ccccc23)cc1OC

InChI Key InChIKey=MEDOEJBMXFGMBH-SOFGYWHQSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50217776   

TargetMelanocyte-stimulating hormone receptor(Mus musculus)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50217776(CHEMBL397324 | N-(2-bromo-4,5-dimethoxycinnamyl)-N...)
Affinity DataKi:  2.00E+3nMAssay Description:Displacement of [125I]NDP-MSH from MC1 receptor in mouse B16 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50217776(CHEMBL397324 | N-(2-bromo-4,5-dimethoxycinnamyl)-N...)
Affinity DataKi:  3.20E+3nMAssay Description:Displacement of [125I]NDP-MSH from human recombinant MC4 receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50217776(CHEMBL397324 | N-(2-bromo-4,5-dimethoxycinnamyl)-N...)
Affinity DataKi:  1.40E+4nMAssay Description:Displacement of [125I]NDP-MSH from human recombinant MC3 receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 5(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50217776(CHEMBL397324 | N-(2-bromo-4,5-dimethoxycinnamyl)-N...)
Affinity DataKi:  2.66E+5nMAssay Description:Displacement of [125I]NDP-MSH from human recombinant MC5 receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed