BDBM50219821 CHEMBL42002

SMILES CCc1ccc2c(ccc(OC)c2n1)C(=O)Nc1c(Cl)cncc1Cl

InChI Key InChIKey=PYEOZIHIJFSCOO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50219821   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Schering-Plough

Curated by ChEMBL
LigandPNGBDBM50219821(CHEMBL42002)
Affinity DataIC50:  43nMAssay Description:Inhibition of Phosphodiesterase 4 from human U937 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Schering-Plough

Curated by ChEMBL
LigandPNGBDBM50219821(CHEMBL42002)
Affinity DataIC50:  43nMAssay Description:Inhibition of PDE4 in Homo sapiens (human) U937 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Rattus norvegicus)
Schering-Plough

Curated by ChEMBL
LigandPNGBDBM50219821(CHEMBL42002)
Affinity DataIC50:  75nMAssay Description:Inhibition of rolipram binding to PDE4 in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed