BDBM50224536 2-(1-benzyl-5-(2-(2-(4-chlorophenyl)-4-methylthiazol-5-yl)ethoxy)-1H-indol-3-yl)-3,3,3-trifluoro-2-hydroxypropanoic acid::CHEMBL401419

SMILES Cc1nc(sc1CCOc1ccc2n(Cc3ccccc3)cc(c2c1)C(O)(C(O)=O)C(F)(F)F)-c1ccc(Cl)cc1

InChI Key InChIKey=ZBOGIGWGXQVSPC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50224536   

TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Heriot-Watt University

Curated by ChEMBL
LigandPNGBDBM50224536(2-(1-benzyl-5-(2-(2-(4-chlorophenyl)-4-methylthiaz...)
Affinity DataIC50:  2.70E+4nMAssay Description:Inhibition of PTP1B expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed