BDBM50229718 CHEMBL4072942

SMILES C1CCN(CC1)c1nc(Nc2ccc(cc2)-c2ccnn2-c2ccccc2)nc(n1)N1CCCCC1

InChI Key InChIKey=VVQZMIKHELEROZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50229718   

TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Beni-Suef University

Curated by ChEMBL
LigandPNGBDBM50229718(CHEMBL4072942)
Affinity DataIC50:  6.42E+3nMAssay Description:Inhibition of ovine COX1 using arachidonic acid as substrate preincubated for 5 mins followed by substrate addition measured after 2 mins by enzyme i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Beni-Suef University

Curated by ChEMBL
LigandPNGBDBM50229718(CHEMBL4072942)
Affinity DataIC50:  1.86E+3nMAssay Description:Inhibition of human COX2 using arachidonic acid as substrate preincubated for 5 mins followed by substrate addition measured after 2 mins by enzyme i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed