BDBM50229724 CHEMBL4063273

SMILES COc1cc(\C=C\C(=O)c2ccc(Nc3nc(nc(n3)N3CCOCC3)N3CCOCC3)cc2)cc(OC)c1OC

InChI Key InChIKey=HTLIOJJNCYRJAH-RUDMXATFSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50229724   

TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Beni-Suef University

Curated by ChEMBL
LigandPNGBDBM50229724(CHEMBL4063273)
Affinity DataIC50:  4.65E+3nMAssay Description:Inhibition of ovine COX1 using arachidonic acid as substrate preincubated for 5 mins followed by substrate addition measured after 2 mins by enzyme i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Beni-Suef University

Curated by ChEMBL
LigandPNGBDBM50229724(CHEMBL4063273)
Affinity DataIC50:  870nMAssay Description:Inhibition of human COX2 using arachidonic acid as substrate preincubated for 5 mins followed by substrate addition measured after 2 mins by enzyme i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed