BDBM50238202 CHEMBL4087025
SMILES Cc1cc(\C=C2/SC(=O)NC2=O)c(C)n1-c1ccc(c(O)c1)-c1ccc(\C=C2/SC(=O)NC2=O)cc1
InChI Key InChIKey=JEBRPMPVMMRWQZ-BIAOHPHYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50238202
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
National Health Research Institutes
Curated by ChEMBL
National Health Research Institutes
Curated by ChEMBL
Affinity DataIC50: 760nMAssay Description:Inhibition of recombinant human MCF7 cells derived His-tagged GAC (L123 to S598 residues) expressed in Escherichia coli C41(DE3)pLysS using glutamine...More data for this Ligand-Target Pair
TargetGlutaminase liver isoform, mitochondrial(Homo sapiens)
National Health Research Institutes
Curated by ChEMBL
National Health Research Institutes
Curated by ChEMBL
Affinity DataIC50: 5.73E+3nMAssay Description:Inhibition of recombinant human His-tagged GAB (P56 to V602 residues) expressed in Escherichia coli C41(DE3)pLysS using glutamine as substrate preinc...More data for this Ligand-Target Pair
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
National Health Research Institutes
Curated by ChEMBL
National Health Research Institutes
Curated by ChEMBL
Affinity DataIC50: 247nMAssay Description:Inhibition of recombinant human His-tagged KGA (L123 to L669 residues) expressed in Escherichia coli BL21(DE3)pLysS using glutamine substrate preincu...More data for this Ligand-Target Pair