BDBM50240213 CHEMBL4085366

SMILES Cc1ncc(NC(=O)c2cccc(c2)C(F)(F)F)cc1NC(=O)c1cncc(c1)-c1cnn(C)c1

InChI Key InChIKey=PLVJXCDUGVPNDW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50240213   

TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Integral Biosciences

Curated by ChEMBL
LigandPNGBDBM50240213(CHEMBL4085366)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of human CSF1R using poly[Glu:Tyr] (4:1) as substrate incubated for 2 hrs in presence of [33gammaP]ATP by P81 ion exchange chromatographic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Integral Biosciences

Curated by ChEMBL
LigandPNGBDBM50240213(CHEMBL4085366)
Affinity DataIC50:  180nMAssay Description:Inhibition of human c-Kit using poly[Glu:Tyr] (4:1) as substrate measured after 2 hrs in presence of [33gammaP]ATP by P18 ion exchange chromatographi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed