BDBM50242059 CHEMBL4076435
SMILES CCCn1c2nc([nH]c2c(=O)n(CCC)c1=O)-c1cnn(CC#Cc2cccc(OC(F)(F)F)c2)c1
InChI Key InChIKey=GGTHYPITPRRLLH-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50242059
Affinity DataKi: 3.60nMAssay Description:Displacement of [3H]-MRS-1754 from human adenosine A2B receptor expressed in HEK293 cell membranes after 90 minsMore data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Antagonist activity at human adenosine A2B receptor expressed in HEK293 cells assessed as inhibition of cAMP productionMore data for this Ligand-Target Pair
Affinity DataKi: 8.80nMAssay Description:Antagonist activity at human adenosine A2B receptor expressed in HEK293 cells assessed as inhibition of NECA-induced increase in cAMP accumulation in...More data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Binding affinity to human adenosine A2B receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 107nMAssay Description:Antagonist activity at human adenosine A2B receptor expressed in mouse NIH/3T3 cells assessed as inhibition of NECA-induced IL-6 releaseMore data for this Ligand-Target Pair
Affinity DataIC50: 90nMAssay Description:Antagonist activity at human adenosine A2B receptor expressed in mouse NIH/3T3 cells assessed as inhibition of NECA-induced IL-6 release incubated fo...More data for this Ligand-Target Pair