BDBM50244849 CHEMBL4083345

SMILES CN(C)C(=O)c1cc2cnc(Nc3ccc(NC(=O)NCCCCCC(=O)NO)cc3)nc2n1C1CCCC1

InChI Key InChIKey=HWCQAMUELSLEQU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50244849   

TargetHistone deacetylase 1(Homo sapiens (Human))
Nankai University

Curated by ChEMBL
LigandPNGBDBM50244849(CHEMBL4083345)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Homo sapiens (Human))
Nankai University

Curated by ChEMBL
LigandPNGBDBM50244849(CHEMBL4083345)
Affinity DataIC50:  8.40nMAssay Description:Inhibition of recombinant human full length N-terminal GST-tagged CDK4/Cyclin-D3 co-expressed in baculovirus infected sf21 cells using Rb substrate i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed