BDBM50246199 CHEMBL488265::N-(4-(3-chloro-4-methoxybenzylamino)-8-(2-hydroxyethyl)-7-methoxyquinazolin-6-yl)acetamide

SMILES COc1ccc(CNc2ncnc3c(CCO)c(OC)c(NC(C)=O)cc23)cc1Cl

InChI Key InChIKey=YZMXAIKXCRWLSJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50246199   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bos taurus)
Chong Kun Dang Research Institute

Curated by ChEMBL
LigandPNGBDBM50246199(CHEMBL488265 | N-(4-(3-chloro-4-methoxybenzylamino...)
Affinity DataIC50:  10nMAssay Description:Inhibition of bovine PDE5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Homo sapiens (Human))
Chong Kun Dang Research Institute

Curated by ChEMBL
LigandPNGBDBM50246199(CHEMBL488265 | N-(4-(3-chloro-4-methoxybenzylamino...)
Affinity DataIC50:  2.43E+4nMAssay Description:Inhibition of human recombinant PDE11More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed