BDBM50247371 CHEMBL454923::N-benzyl-1-(2-chloro-2-phenylethyl)-6-(propylthio)-1H-pyrazolo[3,4-d]pyrimidin-4-amine

SMILES CCCSc1nc(NCc2ccccc2)c2cnn(CC(Cl)c3ccccc3)c2n1

InChI Key InChIKey=PGYXMFATLWTNBT-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50247371   

TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50247371(CHEMBL454923 | N-benzyl-1-(2-chloro-2-phenylethyl)...)
Affinity DataKi:  100nMAssay Description:Inhibition of human recombinant Abl by filter-binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50247371(CHEMBL454923 | N-benzyl-1-(2-chloro-2-phenylethyl)...)
Affinity DataKi:  100nMAssay Description:Inhibition of ABL1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50247371(CHEMBL454923 | N-benzyl-1-(2-chloro-2-phenylethyl)...)
Affinity DataKi:  510nMAssay Description:Inhibition of human recombinant c-Src by filter-binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50247371(CHEMBL454923 | N-benzyl-1-(2-chloro-2-phenylethyl)...)
Affinity DataKi:  513nMAssay Description:Inhibition of SRC (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed