BDBM50248604 (3',5'-dichloro-2,6-dihydroxybiphenyl-4-yl)(phenyl)methanone::CHEMBL460545::US9139546, 28
SMILES Oc1cc(cc(O)c1-c1cc(Cl)cc(Cl)c1)C(=O)c1ccccc1
InChI Key InChIKey=CRNLOOZHRPDURJ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 11 hits for monomerid = 50248604
Affinity DataKi: 2.94nMAssay Description:Binding affinity to human CB2 receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2.94nM ΔG°: -11.8kcal/moleT: 2°CAssay Description:Cell membranes from HEK293 cells transfected with the human CB1 receptor and membranes from CHO-K1 cells transfected with the human CB2 receptor were...More data for this Ligand-Target Pair
Affinity DataKi: 27nMAssay Description:Binding affinity to human CB1 receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 27nM ΔG°: -10.5kcal/moleT: 2°CAssay Description:Cell membranes from HEK293 cells transfected with the human CB1 receptor and membranes from CHO-K1 cells transfected with the human CB2 receptor were...More data for this Ligand-Target Pair
Affinity DataKi: 121nMAssay Description:Displacement of [3H]-CP55940 from CB2 receptor (unknown origin) expressed in CHO cell membranes after 90 mins by liquid scintillation counting analys...More data for this Ligand-Target Pair
Affinity DataKi: 121nMAssay Description:Displacement of [3H]-CP55940 from human recombinant cannabinoid CB2 receptor expressed in HEK cell membranes incubated for 1.5 hrs by liquid scintill...More data for this Ligand-Target Pair
Affinity DataKi: 4.78E+3nMAssay Description:Displacement of [3H]-CP55940 from human recombinant cannabinoid CB1 receptor expressed in HEK cell membranes incubated for 1.5 hrs by liquid scintill...More data for this Ligand-Target Pair
Affinity DataKi: 4.78E+3nMAssay Description:Displacement of [3H]-CP55940 from CB1 receptor (unknown origin) expressed in CHO cell membranes after 90 mins by liquid scintillation counting analys...More data for this Ligand-Target Pair
Affinity DataEC50: 155nMAssay Description:Inverse agonist activity at cannabinoid CB2 receptor in human U2OS cells assessed as induction of beta-arrestin recruitment using CCF4/AM as substrat...More data for this Ligand-Target Pair
Affinity DataEC50: 155nMAssay Description:Inverse agonist activity at human recombinant cannabinoid CB2 receptor expressed in HEK cells transfected with CNG assessed as increase in cAMP level...More data for this Ligand-Target Pair
Affinity DataEC50: 153nMAssay Description:Inverse agonist activity at CB2 receptor (unknown origin) expressed in HEK cells assessed as increase in cAMP production measured at 50 mins by ACTOn...More data for this Ligand-Target Pair