BDBM50248974 3-({2-[(2S)-2-Cyanopyrrolidin-1-yl]-2-oxoethyl}amino)-3-methyl-N-[trans-2-phenylcyclopropyl]butanamide::CHEMBL473166

SMILES CC(C)(CC(=O)N[C@H]1C[C@@H]1c1ccccc1)NCC(=O)N1CCC[C@H]1C#N

InChI Key InChIKey=IZBWMXFFQXEPFB-KSZLIROESA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50248974   

TargetProlyl endopeptidase FAP(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50248974(3-({2-[(2S)-2-Cyanopyrrolidin-1-yl]-2-oxoethyl}ami...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human FAPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50248974(3-({2-[(2S)-2-Cyanopyrrolidin-1-yl]-2-oxoethyl}ami...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human DPP8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50248974(3-({2-[(2S)-2-Cyanopyrrolidin-1-yl]-2-oxoethyl}ami...)
Affinity DataIC50:  85nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50248974(3-({2-[(2S)-2-Cyanopyrrolidin-1-yl]-2-oxoethyl}ami...)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibition of human DPP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed