BDBM50248997 3-({2-[(2S)-2-Cyanopyrrolidin-1-yl]-2-oxoethyl}amino)-3-methyl-N-{2-[4-(trifluoromethyl)phenyl]cyclopropyl}butanamide::CHEMBL473176

SMILES CC(C)(CC(=O)N[C@H]1C[C@@H]1c1ccc(cc1)C(F)(F)F)NCC(=O)N1CCC[C@H]1C#N

InChI Key InChIKey=VWNKXXAPMLZFHW-KSZLIROESA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50248997   

TargetProlyl endopeptidase FAP(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50248997(3-({2-[(2S)-2-Cyanopyrrolidin-1-yl]-2-oxoethyl}ami...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human FAPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50248997(3-({2-[(2S)-2-Cyanopyrrolidin-1-yl]-2-oxoethyl}ami...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human DPP8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50248997(3-({2-[(2S)-2-Cyanopyrrolidin-1-yl]-2-oxoethyl}ami...)
Affinity DataIC50:  85nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50248997(3-({2-[(2S)-2-Cyanopyrrolidin-1-yl]-2-oxoethyl}ami...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human DPP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed