BDBM50249548 CHEMBL475586::cis-(3,3-difluoropyrrolidin-1-yl)((2S,4S)-4-(4-(oxazolo[5,4-b]pyridin-2-yl)piperazin-1-yl)pyrrolidin-2-yl)methanone

SMILES FC1(F)CCN(C1)C(=O)[C@@H]1C[C@@H](CN1)N1CCN(CC1)c1nc2cccnc2o1

InChI Key InChIKey=IKTNUKQMSXPHHO-ZFWWWQNUSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50249548   

TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50249548(CHEMBL475586 | cis-(3,3-difluoropyrrolidin-1-yl)((...)
Affinity DataIC50:  5.20nMAssay Description:Inhibition of human plasma DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50249548(CHEMBL475586 | cis-(3,3-difluoropyrrolidin-1-yl)((...)
Affinity DataIC50:  2.39E+3nMAssay Description:Inhibition of human recombinant DPP8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50249548(CHEMBL475586 | cis-(3,3-difluoropyrrolidin-1-yl)((...)
Affinity DataIC50:  2.88E+3nMAssay Description:Inhibition of human recombinant DPP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed