BDBM50249646 CHEMBL4103135

SMILES COc1cccc(Cn2ccc3nc(N)nc(NCc4cc(C)on4)c23)n1

InChI Key InChIKey=JWVMWQAPXXHMJV-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50249646   

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50249646(CHEMBL4103135)
Affinity DataIC50:  2.30E+3nMAssay Description:Displacement of 3H-dofetilide from human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 7(Homo sapiens (Human))
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50249646(CHEMBL4103135)
Affinity DataEC50:  1nMAssay Description:Agonist activity at TLR7 in human PBMC assessed as induction of IFNalpha-mediated inhibition of HCV genotype 1b RNA replication in human HuH luc/neo ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed