BDBM50249648 CHEMBL523281::Dimethyl-(8-phenyl-2,3,5,6-tetrahydro-1H,4H-13-thia-3a-aza-benzo[de]naphthacen-11-ylidene)-ammonium hexafluoro phosphate
SMILES C[N+](C)=c1ccc2c(-c3ccccc3)c3cc4CCCN5CCCc(c45)c3sc2c1
InChI Key InChIKey=SZLAHMQFHATYMF-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50249648
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
The State University Of New York
Curated by ChEMBL
The State University Of New York
Curated by ChEMBL
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of human MDR1 expressed in MDCK2 cells assessed as enhancement of Calcein-AM uptake treated 30 mins before Calcein-AM challenge measured a...More data for this Ligand-Target Pair
TargetATP-dependent translocase ABCB1(Mus musculus (Mouse))
The State University Of New York
Curated by ChEMBL
The State University Of New York
Curated by ChEMBL
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of verapamil-stimulated ATPase activity of mouse cysteine-less MDR3More data for this Ligand-Target Pair