BDBM50251025 4-Amino-N-(3,5-difluoro-4-hydroxyphenyl)benzenesulfonamide::CHEMBL507525

SMILES Nc1ccc(cc1)S(=O)(=O)Nc1cc(F)c(O)c(F)c1

InChI Key InChIKey=KFCPLBLWUKHLOU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50251025   

TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Aristotle University Of Thessaloniki

Curated by ChEMBL
LigandPNGBDBM50251025(4-Amino-N-(3,5-difluoro-4-hydroxyphenyl)benzenesul...)
Affinity DataIC50:  1.41E+4nMAssay Description:Inhibition of aldose reductase in rat lensesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Aristotle University Of Thessaloniki

Curated by ChEMBL
LigandPNGBDBM50251025(4-Amino-N-(3,5-difluoro-4-hydroxyphenyl)benzenesul...)
Affinity DataIC50:  1.41E+4nMAssay Description:Inhibition of Fischer-344 rat lens ALR2 by least-square analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member A1(Rattus norvegicus)
Aristotle University Of Thessaloniki

Curated by ChEMBL
LigandPNGBDBM50251025(4-Amino-N-(3,5-difluoro-4-hydroxyphenyl)benzenesul...)
Affinity DataIC50:  1.03E+4nMAssay Description:Inhibition of Fischer-344 rat kidney AK1A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed