BDBM50253281 CHEMBL522691::N-(4-Cyanophenylmethyl)-4-(2-diphenyl)-1-piperazinehexanamide
SMILES O=C(CCCCCN1CCN(CC1)c1ccccc1-c1ccccc1)NCc1ccc(cc1)C#N
InChI Key InChIKey=BQEDZLDNNBDKDS-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 19 hits for monomerid = 50253281
Affinity DataKi: 0.580nMAssay Description:Displacement of [3H]LSD from rat cloned 5HT7 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.580nMAssay Description:Binding affinity to rat 5HT7 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.580nMAssay Description:Binding affinity to rat cloned 5HT7 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.580nMAssay Description:Displacement of [3H]-5-CT from human 5-HT7b receptor expressed in HEK293 cells after 1 hrMore data for this Ligand-Target Pair
Affinity DataKi: 0.580nMAssay Description:Displacement of [3H]-5-CT from human 5-HT7 receptor expressed in HEK293 cells after 1 hr by beta-countingMore data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:Displacement of [3H]-5-CT from human cloned 5HT7 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:Displacement of [3H]5-CT from human 5HT7 receptor transfected in HEK293 cells after 60 minsMore data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:Displacement of [3H]-LSD from human 5-HT7 receptor after 1.5 hrs by cell based assayMore data for this Ligand-Target Pair
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 23nMAssay Description:Displacement of [3H]-prazosin from rat brain alpha1 adrenergic receptor after 50 minsMore data for this Ligand-Target Pair
Affinity DataKi: 142nMAssay Description:Displacement of [3H]spiroperidol from human cloned dopamine D2L receptor expressed in rat C6 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 188nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 188nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor expressed in HEK293 cells after 1 hr by beta-countingMore data for this Ligand-Target Pair
Affinity DataKi: 188nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor expressed in HEK293 cells after 1 hrMore data for this Ligand-Target Pair
Affinity DataKi: 242nMAssay Description:Binding affinity to dopamine D2 receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 379nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor after 1.5 hrs by cell based assayMore data for this Ligand-Target Pair
Affinity DataKi: 379nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor transfected in HEK293-EBNA cells after 120 minsMore data for this Ligand-Target Pair
Affinity DataKi: 1.57E+3nMAssay Description:Displacement of [3H]-LSD from human 5-HT6 receptor after 1.5 hrs by cell based assayMore data for this Ligand-Target Pair
Affinity DataKi: >5.00E+3nMAssay Description:Binding affinity to sigma 1 receptor (unknown origin) by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 600nMAssay Description:Agonist activity at 5HT7 receptor assessed as relaxation of substance P-induced Dunkin-Hartley guinea pig ileum contractionMore data for this Ligand-Target Pair