BDBM50256861 CHEMBL4075069

SMILES CCOS(=O)(=O)\C=C\c1ccc(OCc2ccc(COc3ccc(\C=C\S(=O)(=O)OCC)cc3)c(c2)C(=O)Nc2ccc(Oc3cccc(c3)C(F)(F)F)cc2)cc1

InChI Key InChIKey=DACRDBBZZLRWTQ-BQASJOSNSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50256861   

TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50256861(CHEMBL4075069)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of recombinant SHP2 (unknown origin) using pNPP as substrate measured after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50256861(CHEMBL4075069)
Affinity DataIC50:  350nMAssay Description:Inhibition of recombinant PTP1B (unknown origin) expressed in Escherichia coli using pNPP as substrate measured after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50256861(CHEMBL4075069)
Affinity DataIC50:  1.62E+3nMAssay Description:Inhibition of recombinant TCPTP (unknown origin) using pNPP as substrate measured after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed